30 POWERFUL Bible Verses For Depression and Hopelessness

Are there Bible verses for depression?

It depends what you mean.

The Bible is not a dispensary that we come to for our daily dose of inspiration or good feelings. The Bible is primarily the grand story of God’s plan to redeem a people for himself for the glory of his name.

Nevertheless, the Bible does speak directly to the depressed, which is good news for people like me who often find themselves engulfed in the darkness.

So yes, there are Bible verses for depression and hopelessness. These verses shine light into dark places, give hope to the hopeless, and allow the depressed person to have God’s perspective rather than their own dismal view.

If you’re depressed, burn the following verses on your heart. Print them out. Think about them and rejoice in them. They can be life to you.

Now, one thing that’s really important to note as you read these verses. You probably won’t FEEL any different after reading these verses.

There’s this weird idea in some Christian circles that the moment you change your thinking your feelings will also change. That as you read these Bible verses for depression, the gloom will suddenly lift.

This couldn’t be further from the truth, especially when it comes to mental illness. But here’s the good news: all these promises are TRUE. They don’t depend on you. They’re all about God and his mighty works on your behalf.

As you read these, thank God that they’re true, regardless of what you feel.

30 Powerful Bible Verses For Depression

Here are 30 bible verses about depression. May these give you hope and strength as you wait for God to lead you out of the Valley of Darkness.

1. God Will Never Leave You

It is the Lord who goes before you. He will be with you; he will not leave you or forsake you. Do not fear or be dismayed (Deuteronomy 31:8).

Don’t be dismayed because God is with you! Just as he swore to never desert the people of Israel, he will NEVER leave you or forsake you because you are in Christ. You are his child, and like a dad clearing a path through the woods for his small child, so God is going ahead of you, clearing the way.

2. God Will Strengthen You and Uphold You

 …fear not, for I am with you; be not dismayed, for I am your God; I will strengthen you, I will help you, I will uphold you with my righteous right hand (Isaiah 41:10).

In your depression, you feel like you can’t hang on to God. Like your weak and helpless, unable to do anything. Sometimes you can’t even get out of bed. The last thing you feel is “spiritual“.

Good news! You don’t have to hold on to God because he is holding to you. When you fall, he will uphold you with his righteous right hand. When you are weak, he will strengthen you. Even if you don’t have assurance of your salvation, you can be assured that God has a firm hold on you.

The reality is, you ARE weak, you’re just feeling it more acutely now. Take comfort from these Bible verses for depression, because God loves to sustain the weak. God’s grace is sufficient for you, even in these deep, dark times.

3. God Hears Your Cry

I waited patiently for the Lord; he inclined to me and heard my cry.
He drew me up from the pit of destruction, out of the miry bog, and set my feet upon a rock, making my steps secure. He put a new song in my mouth, a song of praise to our God (Psalm 40:1-3).

God hears your cries and sees your tears. He is not ignoring you and his heart breaks over your suffering. He takes no delight in the suffering of his people.

You can be sure that God will respond to your pleas for mercy. Maybe not when you want or in the way you want, but he is your loving, merciful Father, and he can’t ignore the cries of his children. He will put a new song in your mouth and set your feet upon the rock. As you study these Bible verses about depression, know that joy will come in the morning.

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4. The Lord Is Your Shield

But you, O Lord, are a shield about me, my glory, and the lifter of my head (Psalm 3:3).

God is your shield when you are weak, helpless, and hopeless. He is standing over you, guarding you, protecting you, keeping watch over you. Even though you are broken by depression, the almighty God is your shield.

He will lift your head out of the dirt and set you on your feet again. He will move you to sweet places and green pastures. You can trust HIS sustaining, protecting power even though you have no strength in yourself.

5. God Is Near To The Brokenhearted

The Lord is near to the brokenhearted and saves the crushed in spirit.
Many are the afflictions of the righteous, but the Lord delivers him out of them all (Psalm 34:18-19).

When you are sunk into the depths of depression, you feel constantly brokenhearted and crushed in spirit. The soundtrack of your life is in a minor key.

God has a special place in his heart for the brokenhearted and crushed in spirit. When you find yourself under a crushing burden, God draws near to you. He sees you in the midst of your affliction and moves toward you with deliverance. Even though you can’t feel his presence, God is nearer to you now than ever, and he is working on your behalf.

6. The Lord Will Renew Your Strength

…but they who wait for the Lord shall renew their strength; they shall mount up with wings like eagles; they shall run and not be weary; they shall walk and not faint (Isaiah 40:31).

Few things sap your strength like depression or feeling anxious. Everything seems overwhelming and impossible. Even the most mundane acts require a massive amount of effort.

The good news is that God is in the business of giving strength to those who have none. He loves to sustain those who are fainting and give life to those who feel completely depleted. Wait for the Lord and he will give you life.

He has promised to renew your strength even though you don’t feel it now. He has good things in store for you, and these Bible verses for depression are proof!

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7. A Bruised Reed He Will Not Break

…a bruised reed he will not break, and a faintly burning wick he will not quench; he will faithfully bring forth justice (Isaiah 42:3).

A bruised reed is one that that is on the verge of breaking, and a faintly burning wick is a flame that is almost entirely extinguished. That’s a very apt description of depression. You feel as though you’re about to be completely broken or totally extinguished.

And though others may judge you because they don’t understand what you’re experiencing, God most certainly does not.

But doesn’t break bruised reeds or blow out flames that are sputtering and smoking. Rather, he nurtures them and heals them and brings them back to life. God doesn’t despise you in your bruised, broken, smoldering state. Rather, he is near to you, nurturing you and sustaining you.

bible verses for depression and anxiety

8. Come All Who Labor and Are Heavy Laden

Come to me, all who labor and are heavy laden, and I will give you rest. Take my yoke upon you, and learn from me, for I am gentle and lowly in heart, and you will find rest for your souls. For my yoke is easy, and my burden is light (Matthew 11:28-30). 

Jesus gives rest to those who are crushed by the weight of the world. He is gentle and lowly in heart, and he doesn’t rebuke those who find themselves laboring under the overwhelming yoke of depression.

Come to Jesus in your depression and find rest for your soul. Let him carry the heavy end of your burden. Confess your utter weakness and frailty and let him be the burden bearer.

9. Nothing Can Separate You From God

For I am sure that neither death nor life, nor angels nor rulers, nor things present nor things to come, nor powers, nor height nor depth, nor anything else in all creation, will be able to separate us from the love of God in Christ Jesus our Lord (Romans 8:38-39).

When you’re haunted by the specter of depression, you feel very cut off from the love of God. Everything seems dark and bleak, as if there will never be another good thing in your life. You feel as though God has left you to wallow in the mire.

Nothing could be further from the truth. You are not outside of God’s sovereign will and gracious love. Because you are in Christ, nothing can separate you from God’s love. The only way God will stop loving you is if he stops loving Jesus.

Though you may feel alone and unloved, there is absolutely NOTHING, including depression, that can stop God from loving you.

Your body may be a broken down temple, but that doesn’t diminish God’s love for you one bit.

10. The Lord Hears Your Cry

When the righteous cry for help, the Lord hears and delivers them out of all their troubles (Psalm 34:17).

When you are sunk into the valley of depression, it feels like you are totally and completely alone. Like no one cares, like no one is listening. You feel isolated, cut off, and like God has abandoned you.

But has not, and could never abandon you. When you cry to him for help, he hears and delivers. Maybe the deliverance won’t come tomorrow, but make no mistake, it will come. God does not leave his people to wallow and blunder their way through depression and hopelessness.

He hears every cry you utter, sees every tear that rolls down your cheek. You are not alone. You have a good Father who is with you and for you.

11. Hope In God

Why are you cast down, O my soul and why are you in turmoil within me? Hope in God; for I shall again praise him, my salvation and my God (Psalm 42:11).

Depression and hopelessness cause turmoil deep within your soul. You feel crushed, broken, downhearted, overwhelmed, and like there is no hope for tomorrow. But even though it feels like you have no hope for tomorrow, you DO have hope.

Why do you have hope? Because God is your salvation. If your hope depended on you and your ability to pull yourself up, you would have no hope. But your hope depends on God. You shall again praise him, even though it feels like that day will never come. Hope in God and trust him to lead you out of the dark valley you find yourself in.

12. Comforted By God

Blessed be the God and Father of our Lord Jesus Christ, the Father of mercies and God of all comfort, who comforts us in all our affliction, so that we may be able to comfort those who are in any affliction, with the comfort with which we ourselves are comforted by God (2 Corinthians 1:3-4).

When you’re in the midst of a bout of depression or hopelessness or anxiety, it feels like you’re all alone. Like no one understands and like no one cares about you. But there is at least one person who deeply loves you and desires to comfort you, and that is God.

God is the Father of mercies and God of all comfort. Run to him in the midst of your brokenness. Flee to him for comfort and grace and strength. He desires to meet you and to comfort you and refresh you.

Don’t try to make it through the darkness of depression on your own. Run to the God of all comfort. Take shelter in the Father of mercies. He is for you and on your side.

Even More Comforting Bible Verses About Depression

Psalm 30:11 – You have turned for me my mourning into dancing; you have loosed my sackcloth and clothed me with gladness,

Deuteronomy 31:8 – It is the Lord who goes before you. He will be with you; he will not leave you or forsake you. Do not fear or be dismayed.”

Psalm 3:3 – But you, O Lord, are a shield about me, my glory, and the lifter of my head.

Isaiah 40:31  – But they who wait for the Lord shall renew their strength; they shall mount up with wings like eagles; they shall run and not be weary; they shall walk and not faint.

John 10:10 – The thief comes only to steal and kill and destroy. I came that they may have life and have it abundantly.

Philippians 4:13 – I can do all things through him who strengthens me. 

John 16:33 – I have said these things to you, that in me you may have peace. In the world you will have tribulation. But take heart; I have overcome the world.

Scripture Quotes For Depression

Isaiah 41:10 – Fear not, for I am with you; be not dismayed, for I am your God; I will strengthen you, I will help you, I will uphold you with my righteous right hand.

Matthew 11:28 – Come to me, all who labor and are heavy laden, and I will give you rest.

Jeremiah 29:11 – For I know the plans I have for you, declares the Lord, plans for welfare and not for evil, to give you a future and a hope. 

Proverbs 3:5-6 – Trust in the Lord with all your heart, and do not lean on your own understanding. In all your ways acknowledge him, and he will make straight your paths.

Psalm 143:7-8 – Answer me quickly, O Lord! My spirit fails! Hide not your face from me, lest I be like those who go down to the pit. Let me hear in the morning of your steadfast love, for in you I trust. Make me know the way I should go, for to you I lift up my soul. 

Psalm 30:5 – For his anger is but for a moment, and his favor is for a lifetime. Weeping may tarry for the night, but joy comes with the morning.

Bible Verses About Depression and Anxiety

1 Peter 5:7 – Casting all your anxieties on him, because he cares for you.

Psalm 143:7-8 – Answer me quickly, O Lord! My spirit fails! Hide not your face from me, lest I be like those who go down to the pit. Let me hear in the morning of your steadfast love, for in you I trust. Make me know the way I should go, for to you I lift up my soul.

Philippians 4:6-7 – Do not be anxious about anything, but in everything by prayer and supplication with thanksgiving let your requests be made known to God. And the peace of God, which surpasses all understanding, will guard your hearts and your minds in Christ Jesus. 

Psalm 23:4 – Even though I walk through the valley of the shadow of death, I will fear no evil, for you are with me; your rod and your staff, they comfort me.

Romans 8:28 – And we know that for those who love God all things work together for good, for those who are called according to his purpose.

Fear Not The Storm

Charles Spurgeon, who was no stranger to depression, said:

Love letters from heaven are often sent in black-edged envelopes. The cloud that is black with horror is big with mercy. Fear not the storm. It brings healing in its wings and when Jesus is with you in the vessel the tempest only hastens the ship to its desired haven.

In the midst of your depression, all you see are clouds that are black with horror. Remember, it is God himself who controls the storms and Jesus is with you in your boat. You may not feel his nearness and it may seem that he is asleep in the stern, but he is with you nonetheless.

When the moment is right, he will deliver you. Until then, hold fast to these verses.


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